Protein misfolding, oligomerization and aggregation are implicated in a variety of neurodegenerative disorders, including Alzheimer's and Parkinson's diseases. New research sheds light on the process ...

A new mathematical model that describes how proteins self-assemble into stacks known as amyloid fibrils could aid the search for drugs to treat diseases like Alzheimer’s and Parkinson’s. The model, ...

PTIR calculates the rates at which originally monomeric proteins are transformed into aggregates at various temperatures under initial-rate settings. Utilizing SMSLS for identical conditions generates ...

Cancer has been recently shown to be affected by protein clusters, particularly by the aggregation of mutant variants of the tumor suppressor protein p53, which are present in more than half of ...