FDA proposes framework clinical trial designs to guide Bayesian methods, improving efficiency in drug development for rare and pediatric conditions.
The FDA’s new draft guidance on Bayesian methodology signals a shift toward more flexible, data-driven clinical trial designs, enabling sponsors to use prior data and adaptive approaches to improve ...
The Canadian Journal of Statistics / La Revue Canadienne de Statistique, Vol. 46, No. 3 (September/septembre 2018), pp. 399-415 (17 pages) For sparse and high-dimensional data analysis, a valid ...
We adapt a semi-Bayesian hierarchical modeling framework to jointly characterize the space–time variability of seasonal precipitation totals and precipitation extremes across the Northern Great Plains ...