During her chemistry Nobel Prize lecture in 2018, Frances Arnold said, “Today we can for all practical purposes read, write, and edit any sequence of DNA, but we cannot compose it.” That isn’t true ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

NSF CAREER award recipient Tomas Gonzalez-Fernandez, an assistant professor of bioengineering in Lehigh University’s P.C. Rossin College of Engineering and Applied Science, leads research at the ...

A compact Cas12f nuclease shows high editing efficiency in human cells, with structural insights enabling an engineered variant potentially suited for future AAV‑compatible delivery.

The rapid evolution of CRISPR/Cas genome editing has redefined the possibilities of cellular and gene therapy, enabling ...

For the millions of people living with genetic diseases like muscular dystrophy and inherited liver disorders, one of the ...

The CRISPR-Cas gene-editing system has long been the focus of research as a promising tool in genome editing. However, the ...

DALLAS--(BUSINESS WIRE)--Colossal Biosciences, a breakthrough biosciences and genetic engineering company, announced an oversubscribed $60M Series A financing led by Thomas Tull and At One Ventures ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...