The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...

Liver cancer is one of the three deadliest cancers worldwide, and metabolic dysfunction-related cases have become ...

Cilia are evolutionarily conserved, microtubule-based organelles that project from the surface of most eukaryotic cells and play a central role in sensing ...

Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is ...

Chen et al. construct a comprehensive immune landscape of lymphatic malformations (LMs) atlas at single-cell resolution, uncovering pro-inflammatory responses and immune dysfunction characteristic.

A polygenic risk score (PRS) based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study. The risk score, which ...

When the heart’s muscle is weakened or injured due to a heart attack, it can make it hard for the heart to pump enough blood ...

The image shows the cross section mutant brown adipose tissue section with enlarged lipid droplets (yellow) and nucleus (blue) being impinged by multiple mitochondria (red). Mitochondria are ...

T cells sit at the center of modern immunotherapy, yet many of the rules that govern their activation, differentiation, dysfunction (e.g., exhaustion), and ...

Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity-a ...