Causal Cascade of Symptoms on Patient Functioning and Health-Related Quality of Life in Non–Small Cell Lung Cancer and Metastatic Breast Cancer Shallow whole-genome sequencing (sWGS) is a ...

"Now we have a background noise modeling framework that can distinguish between deviations in tumor sequencing data that arise due to inherent noise versus those that arise due to real copy-number ...

Identification of variants influences treatment decisions. Inhibitors of the poly-ADP-ribose polymerase (PARP) system, a pathway for repairing single-stranded DNA breaks, are recommended for tumors ...

NEW YORK--(BUSINESS WIRE)--Paige, a leader in next-generation AI technology, today announced an expansion of Paige PanCancer Detect, the first AI application capable of identifying cancer across a ...

"Our study demonstrates that incorporating copy number variant analysis into exome sequencing workflows increases diagnostic yield in diverse pediatric cohorts," Dr. Ji explains. This approach ...

Genomic analysis of cancer cells revealed comprehensive mechanism of tumorigenesis in human patients. Among the abnormalities discovered so far, CNVs accounted for a great portion of all the ...

Hospital for Sick Children in Toronto researchers are reporting that targeted RNA sequencing can detect clinically actionable alterations in 87% of tumors and provide decisive findings where DNA-seq ...

Long follow-up quality of life outcomes from an investigator-initiated randomized trial of enzalutamide versus abiraterone plus prednisolone in docetaxel-untreated castration-resistant prostate cancer ...

Copy number variation (CNV) refers to an increase or decrease in the number of copies of a DNA sequence in a genome, which can subsequently be implicit in promoting aberrant gene expression patterns ...

Liquid biopsy is increasingly recognized as a promising tool for cancer detection and treatment monitoring, yet its effectiveness is often limited by the extremely low levels of tumor-derived DNA ...