A variety of mutations in lentiviral vector expression systems have been shown to generate a non-integrating phenotype. We studied a novel 12 base-pair U3-long terminal repeats (LTR) integrase (IN) ...
Class II transposable elements transpose via an internally encoded transposase acting on the flanking 5′ and 3′ terminal inverted repeat (TIR) sequences and adjacent DNA that may include subterminal ...
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