Did you know that genes can mask and alter the effects of other genes? Could this process, called epistasis, be a key to understanding complex conditions like Alzheimer’s disease and diabetes?

Jim Manzi has a long post up on epistasis, that is, gene-gene interactions: We could call this process of competing algorithms struggling to find the best solution as fast as possible "meta-evolution" ...

Explore the Shifting Balance Theory and its role in understanding epistasis and evolutionary genetics. , an anthology of recent research on the issue of epistasis and its relationship to evolution.^2 ...

Why evolutionary genetics does not always add up / Edmund D. Brodie III -- Beyond the average : the evolutionary importance of gene interactions and variability of epistatic effects / Patrick C.

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic, has undergone genomic mutations, which have led to the ...

Statistical method developed may be used to identify sites of importance for viral adaptation. A group of investigators report developing a new phylogenetic method for detecting epistasis. They ...

A recent article examines the possibility of using epistasis to predict the outcome of the evolutionary processes, especially when the evolving units are pathogens such as viruses. In biology and ...

We apply new analytical methods to understand the consequences of population bottlenecks for expected additive genetic variance. We analyze essentially all models for multilocus epistasis that have ...

Each week, we answer frequently asked questions about life during the coronavirus crisis. If you have a question you'd like us to consider for a future post, email us at [email protected] with the ...

A recent article in the journal Chaos examines the possibility of using epistasis to predict the outcome of the evolutionary processes, especially when the evolving units are pathogens such as viruses ...