It’s a well-known messenger in the brain: a neurotransmitter dubbed GABA that mellows us out. Drug developers have been tinkering with it for decades, and they’ve scored some big hits, notably Xanax ...

Medically reviewed by Stella Bard, MD Key Takeaways Yoga might boost GABA in the brain. Benzodiazepines can increase the ...

It may be possible to reduce the severity of COVID-19 symptoms with an inexpensive amino acid that could open up new treatment options for patients. GABA is a natural molecule that is available ...

Antiepileptic drugs (AEDs) protect against seizures by modulation of voltage-gated sodium and calcium channels, enhancement of GABA A (γ-aminobutyric acid, type A) receptor-mediated synaptic ...

Researchers at the Indian Institute of Science and collaborators used cryo-EM to decode the molecular architecture of a transporter protein controlling the movement of gamma-aminobutyric acid (GABA).

Research funded by the National Institute on Drug Abuse, the National Institutes of Health, suggests that gamma vinyl-GABA (GVG)--a drug used to treat epilepsy--may prove to be an effective treatment ...

We found that rational combination therapy (2 drugs with different mechanisms of action) was better. An irrational combination (eg, combining 2 sodium-channel blockers, or 2 GABA analogs) was inferior ...

A neurotransmitter previously thought only to calm neurons may also play a role in waking them up, according to a study published in the journal PLOS Biology, a discovery which challenges the textbook ...

Shares of Sage Therapeutics (SAGE) soared more than 20% today after the company announced that the U.S. Food and Drug Administration will allow an expedited development program for one of its most ...

Spinal cord injuries caused by trauma such as traffic accidents or falls can lead to the permanent loss of motor and sensory functions. That is because there is a “brake” in the spinal cord, which ...