The Indigenous peoples of the Bolivian highlands are survivors. For thousands of years they have lived at altitudes of more than two miles, where oxygen is about 35 percent lower than at sea level.

How do cells know what they should become as the body develops? Biological development depends crucially on spatial patterns: the lines that eventually give rise to segments, organs, or markings like ...

Many scientific discoveries are serendipitous—the result of chance. Seeing evolution in action in a cheese cave turned out to be exactly that for Benjamin Wolfe, associate professor of biology, and ...

A newly discovered genetic mutation unique to humans may help explain why we are significantly more vulnerable to cancer than our closest evolutionary relatives. Researchers at the University of ...

Groundbreaking research shows that as men age, harmful genetic mutations in sperm become more common—not just from random chance, but because some are naturally favored. Advanced sequencing revealed ...

MPN-BP transformation is driven by sequential mutations disrupting genomic stability, with TP53 mutations being strong predictors of progression. TP53 mutations confer a selective growth advantage, ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth. The study focused on CTNNB1, a gene that produces the protein β-catenin, ...

A man sits outside and holds a slim menthol cigarette between his fingers. Close-up with focus on the cigarette. The study provided a comprehensive examination of how lifestyle and environmental ...

UCLA Health researchers have created a comprehensive map showing how eight different genetic mutations associated with autism spectrum disorder affect early brain development, providing new insights ...