PanMAN data structures compress pangenomes massively, encode evolutionary histories, and enable scalable analysis of millions of genomes.

Genetic variation describes naturally occurring genetic differences among individuals of the same species. This variation permits flexibility and survival of a population in the face of changing ...

Engineers at UC San Diego have developed a new data structure and compression technique that enables the field of pangenomics ...

There are a number of C. trachomatis gene products that exhibit variability and may modulate disease severity (Figure 3). The major categories of variable chlamydial gene products and their roles in ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...

Earth's biodiversity is in crisis. An imminent "sixth mass extinction" threatens beloved and important wildlife. It also threatens to reduce the amount of genetic diversity—or variation—within species ...

Blood cancer is an umbrella term for a variety of diseases that affect the blood, bone marrow and lymphatic system. Like most ...

Scientist examining genetic testing results on a screen High-grade tumors do not directly evolve from lower-grade ones, but both likely emerge from a common, pre-malignant mutagenic field. A recent ...

A new study from the NIH’s All of Us program is shaking up long-held assumptions by revealing that genetic ancestry rarely aligns with racial labels — and that the interplay between biology and ...