WEHI researchers have discovered a never-before-seen mechanism our bodies use to regulate sugar, in findings that rewrite the ...

Recent studies have uncovered surprising mechanisms in sugar metabolism, from a fleeting intermediate state in glucose ...

Glycogen, a hyperbranched polymer of glucose, plays a central role as an energy reserve across diverse organisms. In Escherichia coli, its biosynthesis is linked not only to energy storage but also to ...

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle against Alzheimer's disease and other forms of dementia: brain sugar metabolism.

A surprising discovery about how brain cells handle sugar could shift how scientists approach dementia and Alzheimer’s treatments. In a new study published in Nature Metabolism, researchers uncovered ...

Researchers at WEHI have discovered that ubiquitin, a protein best known for tagging damaged proteins, can also attach to glycogen and regulate its breakdown. Using a new technique called ...

In a new study published in Nature Metabolism titled “Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction,” researchers from the Buck ...

Glycogen storage diseases (GSDs) constitute a group of inherited metabolic disorders that impair normal glycogen synthesis or degradation, resulting in the accumulation of structurally abnormal ...