SIRF, a method that maps reversed DNA replication forks in single cells, uncovering epigenetic signals linked to replication ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop. Until recently, many fast-changing parts of the human genome remained ...

The work demonstrates the power of ancient DNA to illuminate human biology and medicine in addition to history. A massive ...

Scientists have uncovered a surprising new picture of human origins that challenges the long-held idea of a single ancestral ...

When humans started farming around 10,000 years ago, they reshaped their landscapes, diets, and social structures. A common ...

A landmark Nature study analyzing over 22,000 genomes from ancient and modern individuals across West Eurasia has identified nearly 500 genetic changes driven by natural selection over the past 10,000 ...