Researchers combined protein biomarkers, cfDNA analysis, and machine learning to open opportunities for early-stage ovarian cancer screening and diagnostics. The cfDNA fragmentome is a genome-wide ...
This work reviews CM-cfDNA methods applied to clinical oncology, emphasizing both machine learning (ML) techniques and mechanistic approaches. The latter integrate biological principles, enabling a ...
RR = Relative risk of co-segregation of gene of interest and BRCA1 or 2 compared to gene of interest alone; NS = not significant; Fisher’s exact p-values after Bonferroni correction. This is an ASCO ...
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