Pediatric acute myeloid leukemia (AML) is one of the most common acute leukemias in children. While treatment outcomes have ...

Therapeutic efforts in acute myeloid leukemia (AML) face persistent challenges due to diverse and unstable cell populations within and between tumors. Previous studies have investigated how specific ...

Acute myeloid leukemia (AML) impairs neutrophil maturation in bone marrow, with mature neutrophils decreasing by over 78% in marrow and 89% in blood. AML-exposed neutrophils acquire inflammatory ...

In a study published in the journal Genes & Diseases, researchers from Beckman Research Institute of City of Hope, explored the impact of m 6 A modification on the maturation process of precursor ...

A comprehensive map of aberrant hematopoiesis in people with acute myeloid leukemia defines specific cell states and potential therapeutic targets. The team used their reference map for normal ...