Protein microarrays are one aspect of highly automated, large-scale biological screening technologies, the other is nucleic acid arrays. As DNA arrays reveal their origin in Southern blotting ...
*These authors contributed equally to the preparation of this manuscript. Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility, ...
In this post-genomic era, drug discovery and other basic life science research sectors are increasingly utilizing nucleic acid microarrays for comprehensive gene expression studies. Drug discovery ...
Despite the early promise of easily staining and analyzing hundreds of tumors, several problems remain with respect to the use of TMAs, such as bottlenecks in relation to the grading/evaluation stage ...
Though DNA microarrays let researchers rapidly identify the expression levels of genes associated with diseases and pathways, they say little about how much protein these transcripts produce. A new ...
Expression proteomics determines where and when proteins are expressed and measures their quantities. This qualitative and quantitative approach can compare protein expression across conditions, such ...
A revolution has occurred in the field of pharmaceutical development due to the development of drugs that target membrane proteins. It is estimated that one-third of currently available drugs target G ...