Trojan horse” approach may enable ‘antigen-independent’ therapy with potential to treat cancers not traditionally amenable to immunotherapy.

UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes ...

Stopping cancer cells from entering a soft biomechanical state could help the immune system clear dormant cancer metastasis.

A small number of cancer cells with the ability to change their identities and behaviors appear to be a key driver of cancer ...

A small subpopulation of highly plastic cancer cells has been found to be for cancer progression and treatment resistance.

The result is one molecule that can be both a checkpoint degrader and a cancer vaccine ( Nature 2026, DOI: 10.1038/s41586-025 ...

Using CRISPR-based technologies, the MoDeL team introduces precise genetic modifications in mice, enabling researchers to uncover how mammalian genes maintain health and contribute to disease.

Researchers at the University of Colorado Anschutz Medical Campus have found that respiratory viruses can wake up dormant cancer cells in the lungs. They exposed mice to COVID-19 or the flu. In both ...

A bacterium living quietly in the intestines of a tiny tree frog has done something cancer researchers spend careers chasing: it wiped out established tumors in mice with a single treatment. The ...