A stretch of viral DNA in the mouse genome gives cells in early-stage embryos the potential to become almost any cell type in ...

Scientists have created a 6-legged mouse embryo with an extra pair of hindlimbs at the expense of their external genitalia. But far from creating a monster, this rudimentary rodent provides important ...

Infertility is a major healthcare concern. Understanding the molecular regulators governing fertilization, early embryonic ...

Toward the goal of generating high-quality embryo models in vitro, this study establishes a stepwise protocol to derive trophectoderm-like cells from mouse extended pluripotent stem (EPS) cells. These ...

Magdalena (Magda) Zernicka-Goetz, today a developmental and stem cell biologist at the University of Cambridge and California Institute of Technology, recalled being an artistic child who enjoyed ...

A recent study published in Cell investigates how lamina-associated domains (LADs) contribute to nuclear genome organization in early-stage mouse embryos. Focusing on the zygote and two-cell stages, ...

Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These ...