Scientists have observed signs of rejuvenation in the pancreas, liver, spleen, and blood of mice after applying one cycle of cell reprogramming. To achieve this, the researchers have characterized ...

The capacity of an organism to regenerate depends on cell dedifferentiation followed by proliferation. Mammals, in general, have limited regenerative capacity. Now, a team of researchers at the Salk ...

As with many autoimmune diseases, chronic inflammation is linked to the development of multiple sclerosis (MS), a condition that attacks the sheaths around nerves and can lead to muscle weakness and ...

Astrocytes in the adult brain show cellular plasticity; however, whether they have the potential to generate multiple lineages remains unclear. Here, we perform in vivo screens and identify DLX2 as a ...

It is well known that adding a mixture of four reprogramming molecules (Oct4, Sox2, Klf4 and c-Myc) also known as “Yamanaka factors” to cells can reset epigenetic marks to their original patterns.

The team “shows that eggs that have already begun embryonic development, and are about to divide from the one-cell to two-cell stage, still retain the ability to ‘remodel’ sperm DNA,” Hugh Clarke, a ...

Jonas Salk quietly built the polio vaccine through rigorous, methodical work in Pittsburgh: treating patients, refinin ...

A single protein can reverse the developmental clock on adult brain cells called astrocytes, morphing them into stem-like cells that produce neurons and other cell types, UT Southwestern researchers ...

Scientists led by Dr. Manuel Serrano have observed symptoms of rejuvenation in the pancreas, liver, spleen, and blood of mice after applying one cycle of cell reprogramming To achieve this, the ...