Acute myeloid leukaemia (AML) is mainly characterized by an increase in the number of myeloid cells in the bone marrow and a decrease in mature cells, accounting for 28% of leukaemia cases, with a ...

Aging is a complex, multi-system process that shapes health trajectories and risk for age-related outcomes across the life course. At the same time, aging ...

Efficacy of third-line and later (3L+) therapies post poly (ADP-ribose) polymerase inhibitor (PARPi) exposure in recurrent platinum-sensitive ovarian cancer (PSOC): A pooled clinical trial database ...

Heng et al. apply a multi-omics approach combining analyses of energy metabolism, immune cell composition, and plasma proteomics. They reveal altered energy metabolism and immune profiles, alongside ...

Omics framework of colorectal cancer liver metastasis. Genomic, epigenetic, transcriptomic, proteomic, metabolomic, and microbiomic analyses were performed on tissue from primary colorectal cancer ...

Type 2 diabetes (T2D) is a major chronic metabolic disease worldwide and is especially prevalent in older adults. Although many synthetic drugs are ...