Nature

Investigating endothelial invasion and sprouting behavior in three-dimensional collagen matrices

Seeding a monolayer of primary human endothelial cells on the surface of a polymerized three-dimensional collagen matrix in the presence of pro-angiogenic stimuli allows manipulation and analysis of ...
Nature

Stiffness-controlled three-dimensional extracellular matrices for high-resolution imaging of cell behavior

Regulation of cell functions by the physical properties of the extracellular matrix (ECM) has emerged as a crucial contributor to development and disease. Two specific physical properties of the ECM, ...
Business Wire

Ohio and Michigan High School Scientists Win Regional Siemens Competition at University of Notre Dame for Research on Multidimensional Matrices and Exosome Use for Neurological ...

Peter Tian of Hilliard, Ohio earned the top honors and a $3,000 individual scholarship for research on multidimensional matrices. Research on exosome use for possible neurological disease therapies ...
International Monetary Fund

High-Dimensional Covariance Matrix Estimation: Shrinkage Toward a Diagonal Target

This paper proposes a novel shrinkage estimator for high-dimensional covariance matrices by extending the Oracle Approximating Shrinkage (OAS) of Chen et al. (2009) to target the diagonal elements of ...