As people age, muscles naturally lose mass and strength, a condition known as sarcopenia. The decline can make everyday ...

Muscles make up nearly 40% of the human body and power every move we make, from a child's first steps to recovery after injury. For some, however, muscle development goes awry, leading to weakness, ...

This genetic model suggests otherwise, indicating that coupled gating or other mechanical interactions, rather than CICR, drive activation of uncoupled RyR1 channels. Interestingly, the researchers ...

Researchers have identified the role of the large Maf transcription factor family in regulating fast twitch muscle fibers. A mouse model lacking Maf expression in the skeletal muscles exhibited a ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Fast-twitch fibers help with explosive movements like sprinting and weight lifting. Genetics and training influence the distribution of fast-twitch and slow-twitch muscle fibers. Doing strength ...

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All runners, according to a popular school of training thought, can be divided into two categories: slow-twitch and fast-twitch. Physiologically, this idea rests on pretty shaky ground. The old view ...

Most fitness-minded people have probably heard of fast- and slow-twitch muscle fibers. However, the distinction can be somewhat mysterious, especially in the context of understanding how it relates to ...