Exploring mutations that spontaneously switch on a key brain cell receptor

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...
Ars Technica

Mutations in a non-coding gene associated with intellectual disability

Almost 1,500 genes have been implicated in intellectual disabilities; yet for most people with such disabilities, genetic causes remain unknown. Perhaps this is in part because geneticists have been ...
Science Daily

'Silent' mutations found to have repercussions beyond their own gene

Researchers are adding new evidence to the emerging concept that 'silent' or synonymous mutations may have crucial consequences. Their study showed how a synonymous mutation in one gene can ...
Science Daily

Mutations in noncoding DNA become functional in some cancer-driving genes

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...
New Scientist

DeepMind AI can predict if DNA mutations are likely to be harmful

Artificial intelligence firm Google DeepMind has adapted its AlphaFold system for predicting protein structure to assess whether a huge number of simple mutations are harmful. The adapted system, ...
Wired

Sperm From Older Men Have More Genetic Mutations

Human semen not only accumulates genetic mutations with age; as the percentage of sperm carrying potentially serious mutations increases, so does the risk of developing diseases in offspring. This is ...