From middle school biology we were always taught that the nucleus is the “control center” of the cell, similar to how the brain is the control center of our own bodies. At first glance this makes a ...
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Herpes virus infection softens cell nuclei through internal mechanical changes
A recent international research project has used advanced microscopy techniques and computational modeling to discover why ...
Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...
The investigations of KIT researchers have shown that biomolecular condensates enable fast yet reliable activation of the right genes. “Biomolecular condensates are tiny drops that form in specific ...
DNA, though tightly packed in the nucleus, is constantly threatened by damage from metabolism and external stressors. One particularly severe form of DNA damage is the so-called DNA–protein crosslinks ...
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