The transition of an acute source of pain to a chronic pain pathology is one of the most challenging medical dilemmas to explain, but new research may provide an answer to the long-term maintenance of ...

Nerve fibers were identified in the human uterus more than 80 years ago, but only in the past decade has their association with endometriosis pain been appreciated. The main findings of this study are ...

Pain represents the cardinal symptom of osteoarthritis, yet its intensity, quality, and impact vary dramatically among ...

—A better understanding of migraine pathophysiology highlights the functions of calcitonin gene-related peptide (CGRP), which has a critical role in the central and peripheral pathways leading to ...

Suffering from chronic pain can be both a debilitating and lonely experience. Often unaccompanied by outside markers of distress, an actual diagnosis — whether it be lingering pain from an old injury, ...

Neuropathic pain - abnormal hypersensitivity to stimuli - is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from ...

Pain is a complex emotion with a wide spectrum of sensations spanning from extreme acute physical pain to emotional psychological pain. Chronic pain, in particular, is a significant global burden; ...

Chronic groin pain is a common presentation in sports medicine. It is most often a problem in those sports that involve kicking and twisting movements while running. The morbidity of groin pain should ...

Correspondence to: Professor Refshauge School of Physiotherapy, University of Sydney, PO Box 170, Sydney, NSW 1825, Australia; k.refshauge{at}fhs.usyd.edu.au Low back pain is reviewed in terms of when ...

Radiating pain is pain that travels from one body part to another. It begins in one place then spreads across a bigger area. For example, if you have a herniated disc, you may have pain in your lower ...

Classification of neuropathic pain according to etiology or localization has clear limitations. The discovery of specific molecular and cellular events following experimental nerve injury has raised ...

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