Matching excipients to API properties is essential. Hot-melt extrusion (HME) enables formation of amorphous solid dispersions (ASDs) of crystalline compounds, trapping the molecules in less-stable ...

For drug compounds trying to make their way from the lab to the market, poor solubility is often the kiss of death. It’s one of the most common reasons for a drug candidate to drop out of the ...

Stability is a critical factor in drug formulation, with implications for product quality, lifecycle management, and ...

To win at the drug development game, it’s not enough to show up with a great molecule. Many compounds would stall at the discovery stage without effective ways to get them inside patients. But the ...

Increasing API and formulation complexity and new delivery strategies are driving innovations in taste-masking. The careful design and development of formulated oral drug products are key to ensuring ...