JA Rosenfeld is an employee of Signature Genomic Laboratories, a subsidiary of PerkinElmer, Inc. The authors have no other relevant affiliations or financial involvement with any organization or ...

We report on the validation and implementation of the HumanCytoSNP-12 array (Illumina) (HCS) in prenatal diagnosis. In total, 64 samples were used to validate the Illumina platform (20 with a known ...

We performed noninvasive prenatal screening using whole-genome shotgun sequencing, a method that involves sequencing fragments of DNA that, in the aggregate, represent almost all the genome. This ...

A new test may be better at detecting potentially harmful genetic changes in children before they are born than current methods, researchers say. The test, called a chromosomal microarray, detected ...

A new genetic test using microarray analysis provides a more comprehensive examination of a fetus’s DNA than the currently used karotyping, a study has shown. A clinical trial of 4,400 patients over ...