Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Cells are defined by the genes they express. In human cells, there are thousands of different protein coding genes, and the expression of those genes is carefully orchestrated and controlled by a ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

Johns Hopkins Medicine laboratory scientists say they have developed a potential new way to treat a variety of rare genetic diseases marked by too low levels of specific cellular proteins. To boost ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far ...