The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused immense suffering and economic hardship to millions of people worldwide. To date, the mechanism of infection by SARS-CoV-2 ...
In a recent study published on the bioRxiv* preprint server, researchers assess the Arg-Gly-Asp (RGD) motif-mediated binding of the receptor-binding domain (RBD) of the severe acute respiratory ...
Leuven, Belgium, 20 September 2018 - Oxurion NV (Euronext Brussels: OXUR - formerly known as ThromboGenics), a biopharmaceutical company developing innovative treatments to preserve vision in patients ...
Integrin alphavbeta3 and aminopeptidase N (CD13) are important biomarkers involved in tumor angiogenesis, tumor growth and metastasis. Peptides RGD (Arg-Gly-Asp) and NGR (Asn-Gly-Arg) are the most ...
Cell adhesion to extracellular matrix components such as fibronectin has a complex basis, involving multiple determinants on the molecule that react with discrete cell surface macromolecules. Our ...
Oxurion is left with one last shot at success. The latest drug candidate to flounder in the clinic is THR-687, a pan RGD integrin antagonist that failed a midphase eye disease trial, dragging ...
Thrombospondin is a 420,000-D glycoprotein that has recently been shown to have several properties in common with the members of a class of adhesive proteins. To characterize further the adhesive ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback