The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling ...

A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...

Research on crop stress adaptation in the context of climate change is increasingly pivotal for global food security and agricultural sustainability. As ...

Synthetic lethality may help overcome cancer therapeutic resistance by exploiting tumour vulnerabilities, supported by ...

Researchers have uncovered how metabolic reprogramming contributes to renal fibrosis in IgG4-related disease (IgG4-RD), a systemic immune-mediated disorder. The review, published in a leading journal, ...

Retinal degeneration leads to irreversible vision loss, significantly impacting quality of life. Approximately 19.83 million Americans over 40 have age-related macular degeneration (AMD), a leading ...

Prostate cancer is one of the most common cancers and the second leading cause of cancer-related death in men worldwide. However, the mechanisms controlling the early stages of prostate cancer ...