Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Exosomes are small vesicles, ranging from 30-120 nanometers in diameter, secreted from cells throughout the human body. They are marked on their surface by proteins termed ‘tetraspanins’, aptly named ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Over the last two decades, microscopy has seen unprecedented advances in speed and resolution. However, cellular structures are essentially three-dimensional, and conventional super-resolution ...

Super-resolution microscopy can come in different forms, but structured illumination microscopy (SIM) is one of the more common approaches. In this technique, grid projections are used to increase the ...

Scientists have developed a computational technique that greatly increases the resolution of atomic force microscopy, a specialized type of microscope that 'feels' the atoms at a surface. The method ...

A multimodal imaging study combines cryo-X-ray nanotomography and super-resolution fluorescence microscopy to reveal how protein-coated nanoparticles behave in cells. (Nanowerk Spotlight) The ...