Abnormalities in the structure of chromosomes within someone’s genetic makeup are called structural chromosomal abnormalities. Robertsonian translocations are very rare structural chromosomal ...

Inside of each of your cells are thread-like structures made up of parts called chromosomes. These tightly wound threads are what people mean when they refer to your DNA. It’s a blueprint for cell ...

In about one out of every 800 people, two chromosomes fuse together to form an unusual bond. These are known as Robertsonian chromosomes. It's a mystery that has long stumped scientists. Now, ...

Robertsonian chromosomes are large chromosomes that form when the long arm of a chromosome breaks and fuses with another chromosome. They are the most common type of chromosome rearrangement in humans ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, No. 23 (Jun. 6, 2006), pp. 8786-8791 (6 pages) The telomere and centromere are two specialized structures of ...

We investigated six Robertsonian translocations, including two cases of rob(13q14q), one of rob(14q21q), one of rob(13q22q), and two of rob(21q21q), by means of fluorescencein situ hybridization (FISH ...

Translocation is a genetic abnormality in which part of a chromosome moves to another chromosome. Chromosomes are genetic structures within cells that hold genes. When translocation occurs, it causes ...

Robertsonian translocation is the most common form of chromosomal translocation in humans. It means that two chromosomes, the structures that make up a person’s DNA, join together in an abnormal way.

Robertsonian chromosomes are associated with infertility and Down syndrome, now cutting-edge DNA sequencing technology has unveiled the first comprehensive picture of their genetic rearrangements.