Super-enhancers in cancer cells trigger DNA breaks and error-prone repair cycles

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

The mechanical ratchet: A new mechanism of cell division

Cell division is an essential process for all life on Earth, yet the exact mechanisms by which cells divide during early embryonic development have remained elusive—particularly for egg-laying species ...

Textbooks Challenged: Scientists Discover New Mechanism of Cell Division

Scientists have uncovered a new way embryonic cells divide when conventional mechanisms fail. Cell division underpins all ...
Technology Networks

Critical Coordinator of DNA Repair During Cell Division Identified

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...
EurekAlert!

Centromere protein I, a cell cycle checkpoint gene, accelerates tumor progression via the hippo pathway and mediates immune escape in hepatocellular carcinoma

Cell cycle checkpoint-related genes (CCCRGs) are implicated in the development and progression of hepatocellular carcinoma ...
Science Daily

A hidden cellular cleanup trick could reverse aging

Researchers found that the body’s natural recycling system, the lysosome, plays a vital role in removing the protein that drives premature aging. When this system breaks down, aging speeds up. By ...