Spatial transcriptomics may have just achieved single-cell resolution. Researchers led by Evan Macosko, Fei Chen, and colleagues at the Broad Institute in Cambridge, Massachusetts, bound together ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Understanding cellular function within a given microenvironment is currently an expectation rather than the exception in life sciences research. Cell- and tissue-specific relationships determine ...

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

Spatial biology is poised to become the “next big thing” in omics. On the strength of new technologies, it promises to elevate an ambitious concept—the localization of tissue components at the ...

Researchers have developed a method that can monitor cell activity throughout a tissue at high spatial resolution. This study is one of many trying to increase the spatial resolution of cells in ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

This article describes how spatial omics technologies enhance research capabilities and different methods to perform high-plex spatial omics. Why use spatial methods in science and medicine? Imagine ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...