Researchers developed two computational tools to decode how cells communicate in tissues. sCCIgen creates realistic virtual ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Technological development is key to improving the way hematologic cancer is diagnosed and treated. With this vision, the Josep Carreras Leukemia Research Institute is committed to the creation and ...

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

Saurabh Sinha (center) and his collaborators are advancing the field of spatial transcriptomics with development of InSTAnT. Flanking Sinha are trainees from his lab (left to right), Bhavay Aggarwal ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.

A new study in mice identifies how stress during pregnancy affects fetal brain health, linking maternal immune activation to ...

Spatial maps of various tissues and organs in aging mice have revealed new insights into the aging process. Aging is a process common to many animals; however, the complexity of aging means that there ...