It is the classic monster-movie ending — the lab in shambles, the young scientist dead on the floor and his old mentor sadly pronouncing, “He meddled in things man must learn to leave alone.” There’s ...

Researchers at CSH Laboratory identified an oncogenic SRSF1–AURKA–MYC circuit driving pancreatic ductal adenocarcinoma.

To carry out all of life’s functions, proteins must be produced from instructions carried by genes within DNA and delivered to the cell’s protein-making machinery by messenger RNA. However, to ...

Image: “Like a constellation of atoms” – splicing modulator (purple) bound to a spliceosome subunit. Credit: Professor Vlad Pena. Deciding what we need in our lives and what to cut out is no simple ...