For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

A research team has identified a new mechanism that controls DNA’s ability to replicate—and thereby a cell’s ability to divide.

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During ...

Mouse ES cells present active origin firing and replication forks that progress slowly throughout S phase. These features are integral aspects of genome replication ensuring genome integrity in ES ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

This study found that HBV increases sorafenib and regorafenib resistance in HCCs through upregulation of CD133 and activation of the SRC/STAT3 signaling pathway. Our data provide a potentially key ...