New research suggests that alternative splicing may have an even greater influence on biology than just by creating new protein isoforms. The study shows that the biggest impact of alternative ...

What if a cup of coffee could help treat cancer? Researchers at the Texas A&M Health Institute of Biosciences and Technology ...

Endocrine Effects of Adjuvant Letrozole Compared With Tamoxifen in Hormone-Responsive Postmenopausal Patients With Early Breast Cancer: The HOBOE Trial ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

What do your genes have to do with growing old? Quite a lot. But is it due to the actual DNA, or the way those genes are expressed? KPBS sci-tech reporter Thomas Fudge has more on new research that ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

Scientists identify a "master regulator" that may reset Brain Aging by controlling tau and gene expression in neurons.

By integrating long-read and short-read transcriptomics with whole-genome resequencing, the team uncovered specific transcript variants and genetic ...