Ricky Pearsall and the San Francisco 49ers will play the Indianapolis Colts in Week 16, Monday at 8:15 p.m. ET at Lucas Oil Stadium. Game Time: 8:15 p.m.

In Week 15, Cody White and the Seattle Seahawks will meet the Indianapolis Colts, on Sunday at 4:25 p.m. ET. Game Time: 4:25 p.m.

The Pittsburgh Steelers will host the Indianapolis Colts for a Week 9 AFC matchup. The Colts lead the AFC with a 7-1 record, while the Steelers are 4-3. The game will take place on Sunday, Nov. 2, at Acrisure Stadium in Pittsburgh. Tickets for the game are ...

On the heels of scoring one rushing touchdown, carrying the ball 22 times for 73 yards in his last game, Christian McCaffrey and the San Francisco 49ers will meet the Indianapolis Colts in Week 16, on Monday at 8:15 p.m. ET.

The Las Vegas Raiders (2-6) are back home after a very disappointing two-game road trip that saw them get shut out and blow a 17-point lead. Many have given up hope, especially given the inexcusable fashion in which Las Vegas lost its past two games, but a ...

The Indianapolis Colts (6-1) host the Tennessee Titans (1-6) in NFL Week 8 action on Sunday, Oct. 26, 2025. The National Weather Service forecasts sunny skies and a high in the low 60s. Is the roof open for the Colts vs. Titans game on Sunday, Oct. 26?

The Tennessee Titans try to avoid being swept by the Indianapolis Colts on Oct. 26 at Lucas Oil Stadium. Tennessee (1-6) allowed two touchdowns in 11 seconds in the third quarter en route to a 31-13 loss to Mike Vrabel and the New England Patriots.