Researchers analyzed the role of NUDT5 and its interaction with other proteins in the folate pathway and in regulating purine synthesis.

Cell growth is the most fundamental process in organisms, yet the way in which metabolism determines its rate has long remained unclear. To decipher this mystery, researchers from Earth-Life Science ...

A research team including a scientist of Earth-Life Science Institute (ELSI) at Institute of Science Tokyo, Japan, has identified a novel principle in biology that mathematically explains why the ...

The ability to respond to changing surroundings was once considered exclusive to complex living organisms. Then came ...

By fusing enzyme fragments to antibodies, researchers from the Institute of Science Tokyo, in Japan, developed an innovative ...

Mechanistically, the chemists think that in the presence of the enzyme, there’s a formal hydrogen atom abstraction that is ...

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KRRO-110 produced functional protein in Alpha-1 Antitrypsin Deficiency (AATD) patients —KRRO-110 did not reach projected levels of functional protein following a single administration —Pivoting to ...

Sir2, an enzyme belonging to sirtuins, has been effectively involved in the deacetylation of proteins. A tandem allosteric effect of reactant and product is responsible for the efficient deacetylation ...