In chemical analysis, matrix refers to the components of a sample other than the analyte [1] of interest. The matrix can have a considerable effect on the way the analysis is conducted and …

Matrix effects refer to the significant influence of material properties, such as particle size, component location, density, and porosity, on optical spectroscopy results, particularly in solid …

2 days ago · The matrix effect in analytical chemistry is a fundamental challenge where components in a sample, other than the target substance, interfere with the accuracy of the …

A process called standard addition can often be used to assess whether a sample has a matrix effect. If the sample does have a matrix effect, the standard addition procedure will provide a …

A matrix effect describes the changes observed in the detection or quantification of an analyte when other substances are present in the sample. The implications of this phenomenon are …

Oct 19, 2023 · Matrix effect refers to the loss of analyte signal due to the presence of a matrix such as food, urine, plasma or blood. This signal loss can be quantified by comparing it to the …

This review aims to highlight common challenges associated with matrix effects throughout the entire analytical process with emphasis on gas chromatography-mass spectrometry, liquid …

The combined effect of all components of the sample other than the analyte on the measurement of the quantity. If a specific component can be identified as causing an effect then this is …

In this commentary article, the causes of matrix effects and methods for evaluating, minimizing and/or compensating for them are discussed. A novel concept, matrix effect factor (MEF) …

Sep 22, 2025 · Learn why matrix effects cause recovery results to be offset with real examples and when to correct them using blank-matrix based calibration curves.